Dr. Kruse's primary research interests include investigating how cardiometabolic related
diseases affect endothelial, blood vessel and autonomic function, and determining
how these alterations impact skeletal muscle blood flow, exercise tolerance, and overall
health. Other research interests focus on lifestyle and nutraceutical interventions
that can be used to reduce the incidence of cardiometabolic diseases.
- C Gimblet, N. T., Kruse, K Geasland, J Mickelson, M Sun, P Ten-Eyck, M Sambharia,
M Chonchol, M Rossman, C Linkenmeyer, M Tamura, D Seals, K Hoth, D Jalal (2024). Effect
of curcumin on vascular and cognitive function in chronic kidney disease: A randomized
controlled trial. MDPI Antioxidants.
- C Gimblet, N. T., Kruse, K Geasland, J Michelson, M Sun, S Rehman, L Wendt, P Ten
Eyck, G Pierce, D Jalal (2023). Effect of resveratrol on endothelial function in patients
with diabetic kidney disease: A randomized controlled trial. Clin J Am Soc Nephr..
16;19(2):161-168.
- Kruse, N. T., Buzkova, P., Barzilay, J. I., Valderrabano, R. J., Robbins, J. A., Fink,
H. A. & Jalal, D. I. (2020). Association of skeletal muscle mass, kidney disease and
mortality in older men and women: the cardiovascular health study. Aging 12 (21) 21023-21036.
PMID: 33139582. DOI: 10.18632/aging.
- Kruse, N. T., You, Z., Moreau, K., Kendrick, J. & Jalal, D. (2020). Sex differences
in endothelial function in chronic kidney disease. American Journal of Physiology
- Renal Physiology 319 (1) F33-F40. DOI: 10.1152/ajprenal.00156.2020.
- Kruse, N. T. (2020). ‘Comment on: “The Case for Retiring Flexibility as a Major Component
of Physical Fitness”. (Vols. 50). (7), pp. 1405-1407. Sports Medicine. DOI: 10.1007/s40279-020-01291-y.
- Hughes, W. E., Kruse, N. T., Ueda, K., Feider, A. J., Hanada, S., Bock, J. M. & Casey,
D. P. (2020). Dietary nitrate does not acutely enhance skeletal muscle blood flow
and vasodilation in the lower limbs of older adults during single-limb exercise. European
Journal of Applied Physiology 120 (6) 1357-1369. DOI: 10.1007/s00421-020-04368-8.
- Perrenoud, L., Kruse, N. T., Andrews, E., You, Z., Chonchol, M., Wu, C., Ten Eyck,
P., Zepeda-Orozco, D. & Jalal, D. (2020). Uric Acid Lowering and Biomarkers of Kidney
Damage in CKD Stage 3: A Post Hoc Analysis of a Randomized Clinical Trial. Kidney
Medicine 2 (2) 155-161. DOI: 10.1016/j.xkme.2019.11.007.
- Bock, J. M., Hughes, W. E., Ueda, K., Feider, A. J., Hanada, S., Kruse, N. T., Iwamoto,
E. & Casey, D. P. (2020). Greater α1-adrenergic-mediated vasoconstriction in contracting
skeletal muscle of patients with type 2 diabetes. American Journal of Physiology -
Heart and Circulatory Physiology 319 (4) H797-H807. DOI: 10.1152/AJPHEART.00532.2020.
- Kruse, N. T. (2019). Nutraceuticals as a potential adjunct therapy toward improving
vascular health in CKD. (Vols. 317). (5), pp. R719-R732. American Journal of Physiology
- Regulatory Integrative and Comparative Physiology. DOI: 10.1152/ajpregu.00152.2019.
- Jespersen, T., Kruse, N., Mehta, T., Kuwabara, M., Noureddine, L. & Jalal, D. (2018).
Light wine consumption is associated with a lower odd for cardiovascular disease in
chronic kidney disease. Nutrition, Metabolism and Cardiovascular Diseases 28 (11)
1133-1139. DOI: 10.1016/j.numecd.2018.06.018.
- Kruse, N. T., Hughes, W. E., Benzo, R. M., Carr, L. J. & Casey, D. P. (2018). Workplace
Strategies to Prevent Sitting-induced Endothelial Dysfunction. Medicine and Science
in Sports and Exercise 50 (4) 801-808. DOI: 10.1249/MSS.0000000000001484.
- Hughes, W. E., Kruse, N. T., Ueda, K. & Casey, D. P. (2018). Habitual exercise training
in older adults offsets the age-related prolongation in leg vasodilator kinetics during
single-limb lower body exercise. Journal of Applied Physiology 125 (3) 746-754. DOI:
10.1152/japplphysiol.00235.2018.
- Kruse, N. T. & Scheuermann, B. W. (2017). Cardiovascular Responses to Skeletal Muscle
Stretching: “Stretching” the Truth or a New Exercise Paradigm for Cardiovascular Medicine?.
(Vols. 47). (12), pp. 2507-2520. Sports Medicine. DOI: 10.1007/s40279-017-0768-1.
- Kruse, N. T., Hughes, W. E., Ueda, K. & Casey, D. P. (2017). Vasoconstrictor responsiveness
in contracting human muscle: influence of contraction frequency, contractile work,
and metabolic rate. European Journal of Applied Physiology 117 (8) 1697-1706. DOI:
10.1007/s00421-017-3660-7.
- Hughes, W. E., Kruse, N. T. & Casey, D. P. (2017). Sympathetic nervous system activation
reduces contraction-induced rapid vasodilation in the leg of humans independent of
age. Journal of Applied Physiology 123 (1) 106-115. DOI: 10.1152/japplphysiol.00005.2017.
- Kruse, N. T., Silette, C. R. & Scheuermann, B. W. (2016). Influence of passive stretch
on muscle blood flow, oxygenation and central cardiovascular responses in healthy young
males. American Journal of Physiology - Heart and Circulatory Physiology 310 (9) H1210-H1221.
DOI: 10.1152/ajpheart.00732.2015.
- Kruse, N. T., Barr, M. W., Gilders, R. M., Kushnick, M. R. & Rana, S. R. (2013). Using
a practical approach for determining the most effective stretching strategy in female
college division I volleyball players. Journal of strength and conditioning research
27 (11) 3060-7. PMID: 23442280. DOI: 10.1519/JSC.0b013e31828bf2b6.